))
Rabbit hole dive into AMPK vs. MTOR with Coach Debbie
Manage episode 407377461 series 3559835
Debbie Potts द्वारा प्रदान की गई सामग्री. एपिसोड, ग्राफिक्स और पॉडकास्ट विवरण सहित सभी पॉडकास्ट सामग्री Debbie Potts या उनके पॉडकास्ट प्लेटफ़ॉर्म पार्टनर द्वारा सीधे अपलोड और प्रदान की जाती है। यदि आपको लगता है कि कोई आपकी अनुमति के बिना आपके कॉपीराइट किए गए कार्य का उपयोग कर रहा है, तो आप यहां बताई गई प्रक्रिया का पालन कर सकते हैं https://hi.player.fm/legal।
Today Debbie dives into the delicate role of AMPK and MTOR Pathway. Just as insulin, cortisol, cholesterol, and glucose... MTOR isn't bad. It is the GOLDILOCKS Effect of everything in our body. Our body has it's innate intelligence to maintain homeostasis - fascinating ability to turn up or turn down different mechanisms to keep us functioning at optimal leve- until we do something TOO much or TOO little. The effectiveness of fasting or exercise may also depend on individual factors, including an individual’s health status, age, and metabolic health. Combining both fasting and exercise may have synergistic effects on AMPK activation and overall cellular health. AMPK:
…
continue reading
- Nutrient Sensing: Acts as a cellular energy sensor.
- Activation: Triggered by the depletion of energy stores, resulting in a high AMP/ADP:ATP ratio.
- Effects on Metabolism:
- Increases the oxidation of free fatty acids (FFA) and glucose.
- Reduces cholesterol and fatty acid synthesis.
- Regulation by Nutrients:
- Activated during fasting.
- Suppressed by the presence of carbohydrates and amino acids.
- Role in Cellular Processes:
- Signaling to increase mitochondrial biogenesis.
- Promotes aerobic metabolism.
- Activation: Activated by various signals, including resistance exercise.
- Effects on Protein Synthesis and Growth:
- Increases protein synthesis.
- Contributes to muscle hypertrophy.
- Activation Signals:
- Metabolites of muscle damage.
- Growth hormone (GH).
- Essential amino acids (EAA) and branched-chain amino acids (BCAA).
- Carbohydrates and insulin.
- Inhibition by AMPK: mTORC1 is inhibited by AMPK, creating a reciprocal relationship.
Read the rest of the notes on:
https://debbiepotts.net/ampk-vs-mtor-pathway/
or watch on our YouTube channel
https://www.youtube.com/watch?v=0yUW_-43tOc
What are your thoughts, questions or suggestions? Which rabbit hole are we going to go down next week? Send message to www.debbiepotts.net to Coach Debbie Potts.
100 एपिसोडस
साझा करें
