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Gene Therapy Trials and Tribulations | Stats + Stories Episode 333

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Manage episode 425923847 series 1228032
Stats + Stories and The Stats + Stories Team द्वारा प्रदान की गई सामग्री. एपिसोड, ग्राफिक्स और पॉडकास्ट विवरण सहित सभी पॉडकास्ट सामग्री Stats + Stories and The Stats + Stories Team या उनके पॉडकास्ट प्लेटफ़ॉर्म पार्टनर द्वारा सीधे अपलोड और प्रदान की जाती है। यदि आपको लगता है कि कोई आपकी अनुमति के बिना आपके कॉपीराइट किए गए कार्य का उपयोग कर रहा है, तो आप यहां बताई गई प्रक्रिया का पालन कर सकते हैं https://hi.player.fm/legal
When a gene in the human body goes bad, it can cause illness and disease. Scientists have been working for decades to develop therapies to address faulty genes. In the U.S. gene therapy has been approved as a treatment for illnesses such as cancer, hemophilia, AIDS. However, as researchers explore treatment possibilities. The ethics and costs of such treatments remain a concern. A new book aims to provide an overview of the state of gene therapy development which is the focus of this episode of Stat+Stories with guests Avery McIntosh and Oleksandr Sverdlov. Dr. McIntosh is a drug developer working in rare diseases at Pfizer. He has managed teams of statisticians across study phases and in a variety of drug types and disease areas, including neurology, ophthalmology, infectious disease/ global health, hematology, and oncology. He has published peer-reviewed articles on various topics in drug development and biostatistics, including development of cell and gene therapies and qualification of digital endpoints in neurological diseases. Dr. Sverdlov is a Neuroscience Disease Area Statistical Lead at Novartis. He has been actively involved in methodological research and applications of innovative statistical approaches in drug development. He has co-authored over forty refereed articles, edited two monographs, and co-authored a book ``Mathematical and Statistical Skills in the Biopharmaceutical Industry: A Pragmatic Approach''. His most recent work involves design and analysis of clinical trials evaluating novel digital technologies.
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iconसाझा करें
 
Manage episode 425923847 series 1228032
Stats + Stories and The Stats + Stories Team द्वारा प्रदान की गई सामग्री. एपिसोड, ग्राफिक्स और पॉडकास्ट विवरण सहित सभी पॉडकास्ट सामग्री Stats + Stories and The Stats + Stories Team या उनके पॉडकास्ट प्लेटफ़ॉर्म पार्टनर द्वारा सीधे अपलोड और प्रदान की जाती है। यदि आपको लगता है कि कोई आपकी अनुमति के बिना आपके कॉपीराइट किए गए कार्य का उपयोग कर रहा है, तो आप यहां बताई गई प्रक्रिया का पालन कर सकते हैं https://hi.player.fm/legal
When a gene in the human body goes bad, it can cause illness and disease. Scientists have been working for decades to develop therapies to address faulty genes. In the U.S. gene therapy has been approved as a treatment for illnesses such as cancer, hemophilia, AIDS. However, as researchers explore treatment possibilities. The ethics and costs of such treatments remain a concern. A new book aims to provide an overview of the state of gene therapy development which is the focus of this episode of Stat+Stories with guests Avery McIntosh and Oleksandr Sverdlov. Dr. McIntosh is a drug developer working in rare diseases at Pfizer. He has managed teams of statisticians across study phases and in a variety of drug types and disease areas, including neurology, ophthalmology, infectious disease/ global health, hematology, and oncology. He has published peer-reviewed articles on various topics in drug development and biostatistics, including development of cell and gene therapies and qualification of digital endpoints in neurological diseases. Dr. Sverdlov is a Neuroscience Disease Area Statistical Lead at Novartis. He has been actively involved in methodological research and applications of innovative statistical approaches in drug development. He has co-authored over forty refereed articles, edited two monographs, and co-authored a book ``Mathematical and Statistical Skills in the Biopharmaceutical Industry: A Pragmatic Approach''. His most recent work involves design and analysis of clinical trials evaluating novel digital technologies.
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439 एपिसोडस

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