What Are Short-Chain Fatty Acids and Why Do They Matter for Endo?

This EndoLife

Short chain fatty acids are types of gut friendly fats that are produced when good bacteria in our large intestine eats fibre. So, when healthy bacteria eat let’s say, beans, it will ferment our food, and create gas. Along with that gas, it creates short chain fatty acids.

Short chain fatty acids are one of the key reasons gut health is so important to our overall wellbeing.

Number one is that they are the primary source of food/fuel for the cells in our large intestine. They therefore help to keep our gut barrier intact and strong. When this barrier weakens and holes start to form between our cells, food particles, bacteria and toxins from gram-negative bacteria known as lipopolyscharrides (otherwise known as LPS) can leak through the gut into our blood stream and the surrounding pelvic area.

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Show notes

https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233627/

https://www.nature.com/articles/s41598-018-30114-4#:~:text=Probiotic treatment also significantly enhanced,SCFAs in the gut48.

https://www.healthline.com/nutrition/short-chain-fatty-acids-101#TOC_TITLE_HDR_9

https://monashfodmap.com/blog/dietary-fibre-series-resistant-starch/

https://biosignaling.biomedcentral.com/articles/10.1186/s12964-023-01219-9

https://zoe.com/learn/what-are-short-chain-fatty-acids

https://journals.lww.com/ajg/fulltext/2008/09001/wheat_dextrin,_psyllium,_and_inulin_produce.449.aspx#:~:text=Wheat Dextrin, Psyllium, and Inulin,and Gas Volumes In Vitro

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Produced by Chris Robson