EP 128: Parkinson’s disease and precision medicine with Drs. James Beck and Ignacio Mata

The Genetics Podcast

0:00 Introduction

1:05 Insights into the PD GENEration’s (a programme from the Parkinson's Foundation) milestones and progress points for the upcoming year

3:30 The shifting attitudes and perspectives of neurologists and healthcare workers at the PD GENEration

5:50 Insights into Nacho’s work with the genetics of Parkinson’s disease

10:20 Barriers and facilitators to increasing Latino representation in Parkinson’s disease research, including the return of results process in Latin America

17:30 The PD GENEration’s efforts to increase the participation of ethnic minority groups in genetic studies and research

24:15 How to effectively choose inclusive and accessible clinical sites in Latin America

30:10 Major genes implicated in Parkinson’s disease and the potential for prediction and prevention via screening programmes

36:30 The implications of environmental and genetic risk factors for family members of those living with PD

45:00 Promising programmes in PD research and clinical trials, such as Denali and Biogen’s joint effort to develop small molecule inhibitors of LRRK2

48:40 Best practices for community and patient engagement to speed up the process for clinical trials

54:30 Closing remarks

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