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The Chiropractic Forward Podcast: Evidence-based Chiropractic Advocacy द्वारा प्रदान की गई सामग्री. एपिसोड, ग्राफिक्स और पॉडकास्ट विवरण सहित सभी पॉडकास्ट सामग्री The Chiropractic Forward Podcast: Evidence-based Chiropractic Advocacy या उनके पॉडकास्ट प्लेटफ़ॉर्म पार्टनर द्वारा सीधे अपलोड और प्रदान की जाती है। यदि आपको लगता है कि कोई आपकी अनुमति के बिना आपके कॉपीराइट किए गए कार्य का उपयोग कर रहा है, तो आप यहां बताई गई प्रक्रिया का पालन कर सकते हैं https://hi.player.fm/legal
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Chiropractic Treatment Of Mild Traumatic Brain Injury & New Cancer Treatment Approach

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Manage episode 451342332 series 2291021
The Chiropractic Forward Podcast: Evidence-based Chiropractic Advocacy द्वारा प्रदान की गई सामग्री. एपिसोड, ग्राफिक्स और पॉडकास्ट विवरण सहित सभी पॉडकास्ट सामग्री The Chiropractic Forward Podcast: Evidence-based Chiropractic Advocacy या उनके पॉडकास्ट प्लेटफ़ॉर्म पार्टनर द्वारा सीधे अपलोड और प्रदान की जाती है। यदि आपको लगता है कि कोई आपकी अनुमति के बिना आपके कॉपीराइट किए गए कार्य का उपयोग कर रहा है, तो आप यहां बताई गई प्रक्रिया का पालन कर सकते हैं https://hi.player.fm/legal

CF 354: Chiropractic Treatment Of Mild Traumatic Brain Injury & New Cancer Treatment Approach Today we’re going to talk about Chiropractic Treatment Of Mild Traumatic Brain Injury & New Cancer Treatment Approach But first, here’s that sweet sweet bumper music

Purchase Dr. Williams’s book, a perfect educational tool and chiropractic research reference for the daily practitioner, from the Amazon store TODAY!

Chiropractic evidence-based products

Integrating Chiropractors

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OK, we are back and you have found the Chiropractic Forward Podcast where we are giving evidence-based chiropractic a little personality and making it profitable. We’re not the stuffy, elitist, pretentious kind of research. We’re research talk over a couple of beers. So grab you a bushel. I’m Dr. Jeff Williams and I’m your host for the Chiropractic Forward podcast. I’m so glad you’re spending your time with us learning together. Chiropractors – I’m hiring at my personal clinic. I need talent, ambition, smarts, personality, and easy to get along with associates. If this is you and Amarillo, TX is your speed, send me an email at creekstonecare@gmail.com If you haven’t yet I have a few things you should do.

  • Go to Amazon and check our my book called The Remarkable Truth About Chiropractic: A Unique Journey Into The Research. It’s excellent resource for you and is categorized into sections so the information is easy to find and written in a way that is easy to understand for everyone. It’s on Amazon. That’s the Remarkable Truth About Chiropractic by Jeff Williams.
  • Like our Chiropractic Forward Facebook page,
  • Join our private Chiropractic Forward Facebook group, and then
  • Review our podcast on wherever you listen to it
  • Last thing real quick, we also have an evidence-based brochure and poster store at chiropracticforward.com

You have found yourself smack dab in the middle of Episode #354 Now if you missed last week’s episode, we talked about Head And Neck Cancer & Degenerative Cervical Myelopathy Make sure you don’t miss that info. Keep up with the class.

On the personal end of things…..

Nothing crazy this week. Just in the grind. I think we’re looking at a great week numbers-wise. We’re looking at about 165 or so this week. Maybe more. Hopefully more. Still doing the whack-a-mole thing with our billing and collections company. I don’t know exactly what’s going on with them but we just aren’t collecting much in the last month or so. It’s stressing me. After some time in business, you’ll start to feel a bit like a hamster on a wheel that never ever ends and it’s frustrating and stressful and somewhat maddening. If you describe yourself as a weak-minded person, start working for someone else.

Just listen to your ol Uncle Jeffro on this folks. It ain’t for the faint of heart sometimes. It’s whack-a-mole but with potentially serious implications. Maybe I need to learn some meditation or something like that.

Because you know what I’ve found? At the end of the day, it’s all going to be fine. It all works out. Hell, I lost $750k over a three year period because I had a girl who wasn’t doing her job but was convincing when asked if she was doing her job. Sometimes stats don’t tell the whole story when you’re doing PI work and reducing balances and all that. Anyway, if I can get over a loss like that, you can get over most things in life wouldn’t you agree?

Remember, keep smacking each and every mole as they pop up, take a long weekend trip somewhere at least once per quarter, smile even when you’re sick, tired, don’t feel good, or are just in a bad mood, treat your staff and your family right, give you patients the best evidence-based, patient-centered care, make sure you are always marketing and keeping your eyes out for new treatment techniques and modalities and you should be good to go. Some big news on the VoiceOver side of my life. I recently made two really big moves.

  1. I signed with DPN Talent which is a group out of Beverly Hills and is one of the big five national talent agencies in the US. It’s the major leagues and it’s huge.
  2. This week, I signed with ACM which is a big national management group. So we have agents and management. DPN agent, ACM is management.

When you hear someone’s voice on a Super Bowl commercial or some big campaign or movie trailer or something of that size and stature, you’re probably hearing someone that is with a large national agent or with a large management group like these two I’ve signed with. The point is: things just got really real on the VoiceOver front and Ol Jeffro needs to figure out how to be more available from day to day if needed.

Which bring up one more thing I’ve was talking with our intern, Austin, about recently. Don’t wait until you’re my age to start considering an associate. I could have hired one years ago but my wife was resistant and, honestly……it’s kind of scary. We looked at what it would cost us instead of what it would give us. Having the right associate would give us security should something happen to me and it would give us clinical growth.

I’ve said it before but, for better or worse, I have a big machine that I’ve built with about 11 or 12 employees currently. That’s a lot of mouths to feed every day. I’ve had COVID four and maybe five times and I only missed one day of work. Yes, blast me for going to work sick if you like. I wore my mask and kept my hands washed and all that good stuff but yeah……I know.

Anyway, the point is that that is not fair to me, it’s not fair to patients, it’s not fair to my family, and it’s not fair to my staff for me to not have better systems in place for a machine this size. The entire thing still depends on my presence and suffers a great deal should I have to be gone traveling, sick, or injured.

That’s not good planning on my part and it’s not fair. Not to mention that 155-175 patients every week is exacting a toll on my 52-year-old, former college football-playing body. So, for that reason, I’ve been looking for a good associate that wants to be great. My problem is that nobody wants to move to Amarillo. Which I get but I don’t get. It’s dry. No humidity. Yes it can get hot. It can get up to 105 or so on some days in the Summer but no humidity is real. It makes a difference. Then it can get cold as hell.

The average Winter temp is probably 35-45 degrees. Some warmer some colder. Yes we get 2-3 snows per year. Some major, some not. No there are not a ton of trees and lakes in Amarillo but, we are only 3.5 hours from the ski resorts in New Mexico and only about 5 hours from Colorado Springs, 4 hours to Albuquerque 4 hours to OKC, 5.5 hours to Dallas. And we have a nice little airport to get us where we’re going and there’s about 270k people or more in our immediate region.

So, if you want to give Amarillo some consideration, I hope you will. Email me at creekstonecare@gmail.com and let’s get to know each other. The long-term plan is to hire an associate and get them profitable asap. Then hire another associate and repeat. Once that is in place, you’ll both see less and less of me day to day. Voiceover work is calling and I can’t do it at the level it will require if I’m busy doing the hands-on work of patient treatment all day every day. It’s impossible. So come on y’all. Help a brother out here! Just an offer from your ol Uncle Jeffro.

Item #1

Our first one today is called, “Study raises hopes of treating aggressive cancers by zapping roque DNA” by The Guardian statt and published in November 2024 cheese and rice that’s hot!

Remember, the citations can be found at chiropracticforward.com under this episode.

https://www.theguardian.com/society/2024/nov/06/zapping-rogue-dna-key-treating-aggressive-cancers-study

Bailey, C., Pich, O., Thol, K. et al. Origins and impact of extrachromosomal DNA. Nature 635, 193–200 (2024). https://doi.org/10.1038/s41586-024-08107-3

Tang, J., Weiser, N.E., Wang, G. et al. Enhancing transcription–replication conflict targets ecDNA-positive cancers. Nature 635, 210–218 (2024). https://doi.org/10.1038/s41586-024-07802-5

Hung, K.L., Jones, M.G., Wong, I.TL. et al. Coordinated inheritance of extrachromosomal DNAs in cancer cells. Nature 635, 201–209 (2024). https://doi.org/10.1038/s41586-024-07861-8

This is an article so we’re just hitting the highlights. Scientists have made a promising discovery about treating aggressive cancers by focusing on a unique type of DNA called extrachromosomal DNA (ecDNA). Here are the key points: 1. What is ecDNA?

  • Small, circular DNA fragments that break off from chromosomes
  • Previously thought to be rare and unimportant in cancer development
  • Now recognized as a critical factor in tumor growth and treatment resistance

2. Research Findings:

  • Study analyzed nearly 15,000 UK patients across 39 tumor types
  • 17.1% of tumors contained ecDNA
  • More common in breast, brain, and lung cancers

3. Why ecDNA is Problematic:

  • Carries cancer-driving genes
  • Helps tumors suppress the immune system
  • Allows tumors to replicate rapidly and unevenly, increasing genetic diversity
  • Makes cancers more resistant to traditional treatments

4. Potential Treatment breakthrough:

  • Researchers identified CHK1 inhibitors as a potential targeted treatment
  • Initial mouse experiments showed promise in reducing tumors and preventing drug resistance

The researchers are hopeful this discovery could transform cancer treatment, potentially turning “terrible prognosis into a treatable one” by targeting these unique DNA fragments. The article references three research papers published in Nature, but does not provide the specific citation details. Based on the text, the research was:

  • A collaborative US-UK study
  • Funded by Cancer Grand Challenges (an initiative co-founded by Cancer Research UK and the US National Cancer Institute)
  • Analyzed tumors from nearly 15,000 UK patients
  • Involved researchers including:
    • Paul Mischel (Stanford University)
    • Charles Swanton (Francis Crick Institute)

I’ve seen other cancer papers coming out more recently that really give me a lot of hope that maybe, just maybe with all of the new technology we have access to now, that cancer is about to go the way of polio. We can only hope.

Item #2

The second one is called, “Effect of Chiropractic Intervention on Oculomotor and Attentional Visual Outcomes in Young Adults With Long-Term Mild Traumatic Brain Injury: A Randomized Controlled Trial” by Cade et al and published in the Journal of Manipulative and Physiological Therapeutics on November 4, 2024, and good gravy almighty it’s a hot one, comin’ through.

Effect of Chiropractic Intervention on Oculomotor and Attentional Visual Outcomes in Young Adults With Long-Term Mild Traumatic Brain Injury: A Randomized Controlled Trial Cade, Alice E. et al. Journal of Manipulative & Physiological Therapeutics, Volume 0, Issue 0

Why They Did It This study aimed to establish if chiropractic care can improve oculomotor and cognitive symptoms in individuals with persistent postconcussion syndrome (PPCS). Wait a minute, hold the damn phone, what exactly is PPCS? Well, lemme tell ya: a condition that occurs when symptoms of a concussion continue past the normal recovery period and last for more than three months. Symptoms can include:

  • Physical symptoms, such as headaches, dizziness, nausea, and sensitivity to light and sound
  • Cognitive symptoms, such as difficulty concentrating and memory problems
  • Psychological symptoms, such as depression, anxiety, and irritability
  • Sleep issues, such as insomnia or hypersomnia
  • Sensory symptoms, which can affect vision, hearing, smell, taste, touch, and balance

OK, now that we’re all up to speed…..

How They Did It

A single-blind, randomized controlled intervention study recorded baseline computerized eye-tracker assessment (CEA) outcomes in 40 young adults with PPCS following mild traumatic brain injury. Participants were randomly allocated to either a chiropractic or age-matched active control intervention, and the change in CEA outcomes following intervention was compared between the chiropractic and control groups. A battery of CEAs including egocentric localization, fixation stability, pursuit, saccades, Stroop, and the vestibulo-ocular reflex, were used to assess oculomotor function, visual attention/processing, and selective attention.

What They Found

  • Relative to the control group, participants receiving the chiropractic intervention scored better in the Stroop test, had improved gaze stability during both vestibulo-ocular reflex and fixation stability, and a lower vertical error in egocentric localization.
  • However, performance was poorer in pursuits, where they had an increased tracking error

Wrap It Up

  • Chiropractic care in participants with PPCS significantly improved static and dynamic gaze stability, and performance in the Stroop test, compared with a control intervention.
  • These results suggest that chiropractic care can offer a novel avenue for alleviating certain visual and cognitive symptoms in patients with PPCS.
  • It also adds to the growing evidence that suggests that some longstanding PPCS visual symptoms may have a spinal or proprioceptive basis.

And there you have it, smarter now than before. Y’all have a great week and we’ll see you right here again next week. Alright, that’s it. Keep on keepin’ on. Keep changing our profession from your corner of the world. The world needs evidence-based, patient-centered practitioners driving the bus. The profession needs us in the ACA and involved in leadership of state associations. So quit griping about the profession if you’re doing nothing to make it better. Get active, get involved, and make it happen. Let’s get to the message. Same as it is every week.

Store Remember the evidence-informed brochures and posters at chiropracticforward.com.

Purchase Dr. Williams’s book, a perfect educational tool and chiropractic research reference for the daily practitioner, from the Amazon store TODAY!

Chiropractic evidence-based products

Integrating Chiropractors

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The Message

I want you to know with absolute certainty that when Chiropractic is at its best, you can’t beat the risk vs reward ratio because spinal pain is primarily a movement-related pain and typically responds better to movement-related treatment rather than chemical treatments like pills and shots. When compared to the traditional medical model, research and clinical experience show us patients can get good to excellent results for headaches, neck pain, back pain, and joint pain to name just a few. It’s safe and cost-effective can decrease surgeries & disability and we do it through conservative, non-surgical means with minimal hassle to the patient. And, if the patient treats preventatively after initial recovery, we can usually keep it that way while raising the overall level of health!

Key Point: At the end of the day, patients should have the guarantee of having the best treatment that offers the least harm. When it comes to non-complicated musculoskeletal complaints…. That’s Chiropractic!

Contact Send us an email at dr dot williams at chiropracticforward.com and let us know what you think of our show and tell us your suggestions for future episodes. Feedback and constructive criticism is a blessing and so are subscribes and excellent reviews on podcast platforms. We know how this works by now. If you value something, you have to share it, interact with it, review it, talk about it from time to time, and actively hit a few buttons to support it here and there when asked. It really does make a big difference.

Connect We can’t wait to connect with you again next week. From the Chiropractic Forward Podcast flight deck, this is Dr. Jeff Williams saying upward, onward, and forward.

Website http://www.chiropracticforward.com

Social Media Links https://www.facebook.com/chiropracticforward/

Chiropractic Forward Podcast Facebook GROUP https://www.facebook.com/groups/1938461399501889/

Twitter https://twitter.com/Chiro_Forward

YouTube https://www.youtube.com/channel/UCtc-IrhlK19hWlhaOGld76Q

iTunes https://itunes.apple.com/us/podcast/chiropractic-forward-podcast-chiropractors-practicing/id1331554445?mt=2

Player FM Link https://player.fm/series/2291021

Stitcher: https://www.stitcher.com/podcast/the-chiropractic-forward-podcast-chiropractors-practicing-through

TuneIn https://tunein.com/podcasts/Health–Wellness-Podcasts/The-Chiropractic-Forward-Podcast-Chiropractors-Pr-p1089415/

About the Author & Host Dr. Jeff Williams – Fellow of the International Academy of Neuromusculoskeletal Medicine (FIANM) and Board Certified Diplomate of the American Board of Forensic Professionals (DABFP) – Chiropractor in Amarillo, TX, Chiropractic Advocate, Author, Entrepreneur, Educator, Businessman, Marketer, and Healthcare Blogger & Vlogger

The post Chiropractic Treatment Of Mild Traumatic Brain Injury & New Cancer Treatment Approach appeared first on Chiropractic Forward.

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iconसाझा करें
 
Manage episode 451342332 series 2291021
The Chiropractic Forward Podcast: Evidence-based Chiropractic Advocacy द्वारा प्रदान की गई सामग्री. एपिसोड, ग्राफिक्स और पॉडकास्ट विवरण सहित सभी पॉडकास्ट सामग्री The Chiropractic Forward Podcast: Evidence-based Chiropractic Advocacy या उनके पॉडकास्ट प्लेटफ़ॉर्म पार्टनर द्वारा सीधे अपलोड और प्रदान की जाती है। यदि आपको लगता है कि कोई आपकी अनुमति के बिना आपके कॉपीराइट किए गए कार्य का उपयोग कर रहा है, तो आप यहां बताई गई प्रक्रिया का पालन कर सकते हैं https://hi.player.fm/legal

CF 354: Chiropractic Treatment Of Mild Traumatic Brain Injury & New Cancer Treatment Approach Today we’re going to talk about Chiropractic Treatment Of Mild Traumatic Brain Injury & New Cancer Treatment Approach But first, here’s that sweet sweet bumper music

Purchase Dr. Williams’s book, a perfect educational tool and chiropractic research reference for the daily practitioner, from the Amazon store TODAY!

Chiropractic evidence-based products

Integrating Chiropractors

This image has an empty alt attribute; its file name is Screen-Shot-2018-07-12-at-10.23.22-AM-150x55.jpg

This image has an empty alt attribute; its file name is Screen-Shot-2018-07-12-at-10.23.33-AM-150x55.jpg

This image has an empty alt attribute; its file name is Screen-Shot-2018-07-12-at-10.23.09-AM-150x55.jpg

OK, we are back and you have found the Chiropractic Forward Podcast where we are giving evidence-based chiropractic a little personality and making it profitable. We’re not the stuffy, elitist, pretentious kind of research. We’re research talk over a couple of beers. So grab you a bushel. I’m Dr. Jeff Williams and I’m your host for the Chiropractic Forward podcast. I’m so glad you’re spending your time with us learning together. Chiropractors – I’m hiring at my personal clinic. I need talent, ambition, smarts, personality, and easy to get along with associates. If this is you and Amarillo, TX is your speed, send me an email at creekstonecare@gmail.com If you haven’t yet I have a few things you should do.

  • Go to Amazon and check our my book called The Remarkable Truth About Chiropractic: A Unique Journey Into The Research. It’s excellent resource for you and is categorized into sections so the information is easy to find and written in a way that is easy to understand for everyone. It’s on Amazon. That’s the Remarkable Truth About Chiropractic by Jeff Williams.
  • Like our Chiropractic Forward Facebook page,
  • Join our private Chiropractic Forward Facebook group, and then
  • Review our podcast on wherever you listen to it
  • Last thing real quick, we also have an evidence-based brochure and poster store at chiropracticforward.com

You have found yourself smack dab in the middle of Episode #354 Now if you missed last week’s episode, we talked about Head And Neck Cancer & Degenerative Cervical Myelopathy Make sure you don’t miss that info. Keep up with the class.

On the personal end of things…..

Nothing crazy this week. Just in the grind. I think we’re looking at a great week numbers-wise. We’re looking at about 165 or so this week. Maybe more. Hopefully more. Still doing the whack-a-mole thing with our billing and collections company. I don’t know exactly what’s going on with them but we just aren’t collecting much in the last month or so. It’s stressing me. After some time in business, you’ll start to feel a bit like a hamster on a wheel that never ever ends and it’s frustrating and stressful and somewhat maddening. If you describe yourself as a weak-minded person, start working for someone else.

Just listen to your ol Uncle Jeffro on this folks. It ain’t for the faint of heart sometimes. It’s whack-a-mole but with potentially serious implications. Maybe I need to learn some meditation or something like that.

Because you know what I’ve found? At the end of the day, it’s all going to be fine. It all works out. Hell, I lost $750k over a three year period because I had a girl who wasn’t doing her job but was convincing when asked if she was doing her job. Sometimes stats don’t tell the whole story when you’re doing PI work and reducing balances and all that. Anyway, if I can get over a loss like that, you can get over most things in life wouldn’t you agree?

Remember, keep smacking each and every mole as they pop up, take a long weekend trip somewhere at least once per quarter, smile even when you’re sick, tired, don’t feel good, or are just in a bad mood, treat your staff and your family right, give you patients the best evidence-based, patient-centered care, make sure you are always marketing and keeping your eyes out for new treatment techniques and modalities and you should be good to go. Some big news on the VoiceOver side of my life. I recently made two really big moves.

  1. I signed with DPN Talent which is a group out of Beverly Hills and is one of the big five national talent agencies in the US. It’s the major leagues and it’s huge.
  2. This week, I signed with ACM which is a big national management group. So we have agents and management. DPN agent, ACM is management.

When you hear someone’s voice on a Super Bowl commercial or some big campaign or movie trailer or something of that size and stature, you’re probably hearing someone that is with a large national agent or with a large management group like these two I’ve signed with. The point is: things just got really real on the VoiceOver front and Ol Jeffro needs to figure out how to be more available from day to day if needed.

Which bring up one more thing I’ve was talking with our intern, Austin, about recently. Don’t wait until you’re my age to start considering an associate. I could have hired one years ago but my wife was resistant and, honestly……it’s kind of scary. We looked at what it would cost us instead of what it would give us. Having the right associate would give us security should something happen to me and it would give us clinical growth.

I’ve said it before but, for better or worse, I have a big machine that I’ve built with about 11 or 12 employees currently. That’s a lot of mouths to feed every day. I’ve had COVID four and maybe five times and I only missed one day of work. Yes, blast me for going to work sick if you like. I wore my mask and kept my hands washed and all that good stuff but yeah……I know.

Anyway, the point is that that is not fair to me, it’s not fair to patients, it’s not fair to my family, and it’s not fair to my staff for me to not have better systems in place for a machine this size. The entire thing still depends on my presence and suffers a great deal should I have to be gone traveling, sick, or injured.

That’s not good planning on my part and it’s not fair. Not to mention that 155-175 patients every week is exacting a toll on my 52-year-old, former college football-playing body. So, for that reason, I’ve been looking for a good associate that wants to be great. My problem is that nobody wants to move to Amarillo. Which I get but I don’t get. It’s dry. No humidity. Yes it can get hot. It can get up to 105 or so on some days in the Summer but no humidity is real. It makes a difference. Then it can get cold as hell.

The average Winter temp is probably 35-45 degrees. Some warmer some colder. Yes we get 2-3 snows per year. Some major, some not. No there are not a ton of trees and lakes in Amarillo but, we are only 3.5 hours from the ski resorts in New Mexico and only about 5 hours from Colorado Springs, 4 hours to Albuquerque 4 hours to OKC, 5.5 hours to Dallas. And we have a nice little airport to get us where we’re going and there’s about 270k people or more in our immediate region.

So, if you want to give Amarillo some consideration, I hope you will. Email me at creekstonecare@gmail.com and let’s get to know each other. The long-term plan is to hire an associate and get them profitable asap. Then hire another associate and repeat. Once that is in place, you’ll both see less and less of me day to day. Voiceover work is calling and I can’t do it at the level it will require if I’m busy doing the hands-on work of patient treatment all day every day. It’s impossible. So come on y’all. Help a brother out here! Just an offer from your ol Uncle Jeffro.

Item #1

Our first one today is called, “Study raises hopes of treating aggressive cancers by zapping roque DNA” by The Guardian statt and published in November 2024 cheese and rice that’s hot!

Remember, the citations can be found at chiropracticforward.com under this episode.

https://www.theguardian.com/society/2024/nov/06/zapping-rogue-dna-key-treating-aggressive-cancers-study

Bailey, C., Pich, O., Thol, K. et al. Origins and impact of extrachromosomal DNA. Nature 635, 193–200 (2024). https://doi.org/10.1038/s41586-024-08107-3

Tang, J., Weiser, N.E., Wang, G. et al. Enhancing transcription–replication conflict targets ecDNA-positive cancers. Nature 635, 210–218 (2024). https://doi.org/10.1038/s41586-024-07802-5

Hung, K.L., Jones, M.G., Wong, I.TL. et al. Coordinated inheritance of extrachromosomal DNAs in cancer cells. Nature 635, 201–209 (2024). https://doi.org/10.1038/s41586-024-07861-8

This is an article so we’re just hitting the highlights. Scientists have made a promising discovery about treating aggressive cancers by focusing on a unique type of DNA called extrachromosomal DNA (ecDNA). Here are the key points: 1. What is ecDNA?

  • Small, circular DNA fragments that break off from chromosomes
  • Previously thought to be rare and unimportant in cancer development
  • Now recognized as a critical factor in tumor growth and treatment resistance

2. Research Findings:

  • Study analyzed nearly 15,000 UK patients across 39 tumor types
  • 17.1% of tumors contained ecDNA
  • More common in breast, brain, and lung cancers

3. Why ecDNA is Problematic:

  • Carries cancer-driving genes
  • Helps tumors suppress the immune system
  • Allows tumors to replicate rapidly and unevenly, increasing genetic diversity
  • Makes cancers more resistant to traditional treatments

4. Potential Treatment breakthrough:

  • Researchers identified CHK1 inhibitors as a potential targeted treatment
  • Initial mouse experiments showed promise in reducing tumors and preventing drug resistance

The researchers are hopeful this discovery could transform cancer treatment, potentially turning “terrible prognosis into a treatable one” by targeting these unique DNA fragments. The article references three research papers published in Nature, but does not provide the specific citation details. Based on the text, the research was:

  • A collaborative US-UK study
  • Funded by Cancer Grand Challenges (an initiative co-founded by Cancer Research UK and the US National Cancer Institute)
  • Analyzed tumors from nearly 15,000 UK patients
  • Involved researchers including:
    • Paul Mischel (Stanford University)
    • Charles Swanton (Francis Crick Institute)

I’ve seen other cancer papers coming out more recently that really give me a lot of hope that maybe, just maybe with all of the new technology we have access to now, that cancer is about to go the way of polio. We can only hope.

Item #2

The second one is called, “Effect of Chiropractic Intervention on Oculomotor and Attentional Visual Outcomes in Young Adults With Long-Term Mild Traumatic Brain Injury: A Randomized Controlled Trial” by Cade et al and published in the Journal of Manipulative and Physiological Therapeutics on November 4, 2024, and good gravy almighty it’s a hot one, comin’ through.

Effect of Chiropractic Intervention on Oculomotor and Attentional Visual Outcomes in Young Adults With Long-Term Mild Traumatic Brain Injury: A Randomized Controlled Trial Cade, Alice E. et al. Journal of Manipulative & Physiological Therapeutics, Volume 0, Issue 0

Why They Did It This study aimed to establish if chiropractic care can improve oculomotor and cognitive symptoms in individuals with persistent postconcussion syndrome (PPCS). Wait a minute, hold the damn phone, what exactly is PPCS? Well, lemme tell ya: a condition that occurs when symptoms of a concussion continue past the normal recovery period and last for more than three months. Symptoms can include:

  • Physical symptoms, such as headaches, dizziness, nausea, and sensitivity to light and sound
  • Cognitive symptoms, such as difficulty concentrating and memory problems
  • Psychological symptoms, such as depression, anxiety, and irritability
  • Sleep issues, such as insomnia or hypersomnia
  • Sensory symptoms, which can affect vision, hearing, smell, taste, touch, and balance

OK, now that we’re all up to speed…..

How They Did It

A single-blind, randomized controlled intervention study recorded baseline computerized eye-tracker assessment (CEA) outcomes in 40 young adults with PPCS following mild traumatic brain injury. Participants were randomly allocated to either a chiropractic or age-matched active control intervention, and the change in CEA outcomes following intervention was compared between the chiropractic and control groups. A battery of CEAs including egocentric localization, fixation stability, pursuit, saccades, Stroop, and the vestibulo-ocular reflex, were used to assess oculomotor function, visual attention/processing, and selective attention.

What They Found

  • Relative to the control group, participants receiving the chiropractic intervention scored better in the Stroop test, had improved gaze stability during both vestibulo-ocular reflex and fixation stability, and a lower vertical error in egocentric localization.
  • However, performance was poorer in pursuits, where they had an increased tracking error

Wrap It Up

  • Chiropractic care in participants with PPCS significantly improved static and dynamic gaze stability, and performance in the Stroop test, compared with a control intervention.
  • These results suggest that chiropractic care can offer a novel avenue for alleviating certain visual and cognitive symptoms in patients with PPCS.
  • It also adds to the growing evidence that suggests that some longstanding PPCS visual symptoms may have a spinal or proprioceptive basis.

And there you have it, smarter now than before. Y’all have a great week and we’ll see you right here again next week. Alright, that’s it. Keep on keepin’ on. Keep changing our profession from your corner of the world. The world needs evidence-based, patient-centered practitioners driving the bus. The profession needs us in the ACA and involved in leadership of state associations. So quit griping about the profession if you’re doing nothing to make it better. Get active, get involved, and make it happen. Let’s get to the message. Same as it is every week.

Store Remember the evidence-informed brochures and posters at chiropracticforward.com.

Purchase Dr. Williams’s book, a perfect educational tool and chiropractic research reference for the daily practitioner, from the Amazon store TODAY!

Chiropractic evidence-based products

Integrating Chiropractors

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The Message

I want you to know with absolute certainty that when Chiropractic is at its best, you can’t beat the risk vs reward ratio because spinal pain is primarily a movement-related pain and typically responds better to movement-related treatment rather than chemical treatments like pills and shots. When compared to the traditional medical model, research and clinical experience show us patients can get good to excellent results for headaches, neck pain, back pain, and joint pain to name just a few. It’s safe and cost-effective can decrease surgeries & disability and we do it through conservative, non-surgical means with minimal hassle to the patient. And, if the patient treats preventatively after initial recovery, we can usually keep it that way while raising the overall level of health!

Key Point: At the end of the day, patients should have the guarantee of having the best treatment that offers the least harm. When it comes to non-complicated musculoskeletal complaints…. That’s Chiropractic!

Contact Send us an email at dr dot williams at chiropracticforward.com and let us know what you think of our show and tell us your suggestions for future episodes. Feedback and constructive criticism is a blessing and so are subscribes and excellent reviews on podcast platforms. We know how this works by now. If you value something, you have to share it, interact with it, review it, talk about it from time to time, and actively hit a few buttons to support it here and there when asked. It really does make a big difference.

Connect We can’t wait to connect with you again next week. From the Chiropractic Forward Podcast flight deck, this is Dr. Jeff Williams saying upward, onward, and forward.

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About the Author & Host Dr. Jeff Williams – Fellow of the International Academy of Neuromusculoskeletal Medicine (FIANM) and Board Certified Diplomate of the American Board of Forensic Professionals (DABFP) – Chiropractor in Amarillo, TX, Chiropractic Advocate, Author, Entrepreneur, Educator, Businessman, Marketer, and Healthcare Blogger & Vlogger

The post Chiropractic Treatment Of Mild Traumatic Brain Injury & New Cancer Treatment Approach appeared first on Chiropractic Forward.

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