Episode 15. Management of Newly Diagnosed DLBCL (Including Bonus ASH22 Updates)

Blood Cancer Talks

Rajshekhar Chakraborty and Ashwin Kishtagari, Rajshekhar Chakraborty, Ashwin Kishtagari, and Edward Cliff द्वारा प्रदान की गई सामग्री. एपिसोड, ग्राफिक्स और पॉडकास्ट विवरण सहित सभी पॉडकास्ट सामग्री Rajshekhar Chakraborty and Ashwin Kishtagari, Rajshekhar Chakraborty, Ashwin Kishtagari, and Edward Cliff या उनके पॉडकास्ट प्लेटफ़ॉर्म पार्टनर द्वारा सीधे अपलोड और प्रदान की जाती है। यदि आपको लगता है कि कोई आपकी अनुमति के बिना आपके कॉपीराइट किए गए कार्य का उपयोग कर रहा है, तो आप यहां बताई गई प्रक्रिया का पालन कर सकते हैं https://hi.player.fm/legal।

1+ y ago 53:44

MP3•एपिसोड होम

In this episode, we discuss the management of newly diagnosed DLBCL with Dr. Pallawi Torka. We also have a few bonus ASH22 updates on DLBCL. Links to articles and abstracts discussed in the episode are as follows:

1. A comprehensive review article on DLBCL:

https://pubmed.ncbi.nlm.nih.gov/33657296/

2. RCT testing CHOP vs Three Intensive Regimens in DLBCL:

https://www.nejm.org/doi/full/10.1056/nejm199304083281404

3. RCT testing R-CHOP vs CHOP in DLBCL in older adults:

https://www.nejm.org/doi/full/10.1056/nejmoa011795

4. RCT testing R-CHOP vs CHOP in young (MINT):

https://pubmed.ncbi.nlm.nih.gov/21940214/

5. PHOENIX trial: R-CHOP +/- Ibrutinib:

https://pubmed.ncbi.nlm.nih.gov/30901302/

6. R-CHOP +/- Lenalidomide (ECOG-ACRIN E1412):

https://pubmed.ncbi.nlm.nih.gov/33555941/

7. R-CHOP vs Pola-R-CHP (POLARIX Trial):

https://www.nejm.org/doi/full/10.1056/NEJMoa2115304

8. Comparison of 3 IPI scores in DLBCL:

https://ashpublications.org/blood/article/135/23/2041/452696

9. RCT testing R-CHOP vs Dose-Adjusted R-EPOCH (CALGB 50303):

https://ascopubs.org/doi/full/10.1200/JCO.18.01994

10. Timing of CNS Prophylaxis in DLBCL:

https://pubmed.ncbi.nlm.nih.gov/34995350/

11. RCT testing R-CHOP vs R-CHOP + Bortezomib (REMoDL-B):

https://pubmed.ncbi.nlm.nih.gov/30948276/

12. Interim PET in DLBCL?

https://ashpublications.org/bloodadvances/article/5/9/2375/475850

13. RCTs in Limited Stage DLBCL:

CHOP x 8 vs CHOP x 3 + XRT (S8736):

https://ascopubs.org/doi/10.1200/JCO.2015.65.4582

CHOP x 4 + Rituximab x 6 vs R-CHOP x 6 (FLYER):

https://pubmed.ncbi.nlm.nih.gov/31868632/

PET-adapted therapy with R-CHOP (S1001):

https://pubmed.ncbi.nlm.nih.gov/32658627/

14. ASH 2022 updates:

REMoDL-B update: https://ashpublications.org/blood/article/140/Supplement%201/1770/493225

Glofitamab update: https://ashpublications.org/blood/article/140/Supplement%201/1062/491024

Epcoritamab update: https://ashpublications.org/blood/article/140/Supplement%201/9443/488543

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