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Iron Matters

Haemochromatosis Australia

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IRON-MATTERS is a series of interviews by and for medical and health practitioners focusing on hereditary haemochromatosis. The series is intended to provide general practitioners with in-depth information about this genetic chronic condition. Topics include - diagnosis in general practice with GP Dr Robert Menz- the genetics of haemochromatosis with clinical geneticist Prof martin Delatycki- haemochromatosis and the liver with gastroenterologist Prof John Olynyk- haemochromatotic arthropath ...
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Lan-Lan Smith, Editor-in-Chief, and Emma Cookson, Senior Editor at The Lancet Haematology, in conversation with the journal’s authors, explore their latest research and its impact on people’s health, healthcare, and health policy. A monthly audio companion to the journal, this podcast covers a broad range of topics, from racial and ethnic disparities in leukaemia survival outcomes to resuscitation with blood products compared with saline, the link between mental health and lymphoma to haemol ...
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The Healthy Family Podcast

Maryann Jacobsen: Registered Dietitian, Family Nutrition & Health Expert, Independent Author

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Take a ride with family nutrition expert Maryann Jacobsen as she deconstructs what it really means to be healthy and happy at all ages and stages. Whether it’s an expert she’s interviewing for her latest book, a health-related topic families need to know about, or the latest nutrition news, you’ll be glad you tuned in. Each episode arms you with credible information, expert advice, and modern-day strategies for creating a healthy family in the 21st century.
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Professor Matteo Giovanni Della Porta joins us to discuss the primary analysis of the phase 3 COMMANDS trial comparing luspatercept versus epoetin alfa in erythropoiesis-stimulating agent-naive, transfusion-dependent, lower-risk myelodysplastic syndrome patients. Continue this conversation on social! Follow us today at... https://twitter.com/thelan…
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Dr Kim Linton joins us to discuss the EPCORE NHL-1 trial testing monotherapy with the bispecific antibody epcoritamab for patients with relapsed or refractory follicular lymphoma. Read the full article: https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(24)00166-2?dgcid=buzzsprout_tlv_podcast_generic_lanhae Continue this conversation o…
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Dr Judy Truong join us to discuss ferritin reference intervals and how adoption of evidence-based ferritin clinical decision limits can help clinicians detect and treat iron deficiency, minimising propagation of related health inequity and social injustice in medicine. Read the full article: https://www.thelancet.com/journals/lanhae/article/PIIS235…
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Professor Johannes Schetelig joins us to discuss the results of the ASAP phase 3 trial comparing remission induction with immediate allogeneic haematopoietic stem cell transplantation for patients with relapsed or poor responsive acute myeloid leukaemia. Read the full article: https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(24)00065…
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Professor Banu Aygun joins us to discuss the REACH trial testing hydroxyurea dose optimisation for children with sickle cell anaemia in sub-Saharan Africa. Read the full article: https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(24)00078-4?dgcid=buzzsprout_icw_podcast_generic_lanhae Continue this conversation on social! Follow us toda…
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Dr Sabine Braat and Dr Katherine Fielding join us to discuss their study presenting new haemoglobin thresholds for defining anaemia. Read the full article: https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(24)00030-9/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhae Continue this conversation on social! Follow us today at... https:…
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Doctor Elisabeth Schorb joins us to discuss the MARTA phase 2 trial, treating older, fit patients with primary diffuse large B-cell CNS lymphoma with high-dose chemotherapy and autologous stem-cell transplantation. Read the full article: https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00371-X/fulltext?dgcid=buzzsprout_icw_podcast…
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Professor Stephan Ehl joins us to discuss a prospective observational study on paediatric autoimmune lymphoproliferative immunodeficiencies. Read the full article: https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00638-1/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanonc Continue this conversation on social! Follow us today at..…
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Dr Sarah O'Brien joins Lan-Lan Smith to discuss results of the phase 3 PREVAPIX-ALL trial, which compares direct oral anticoagulant apixaban to low-molecular-weight-heparin for the prevention of venous thromboembolism in children with newly diagnosed acute lymphoblastic leukaemia or lymphoma. Read the full article: https://www.thelancet.com/journal…
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Professor Enrico Lopriore joins us to discuss a trial testing darbepoetin alfa to prevent postnatal anaemia in infants with haemolytic disease of the fetus and newborn. Read the full article: https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00285-5/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhae Continue this conversation on …
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Professor Meletios Dimopoulos joins us to discuss two trials for patients with relapsed and refractory multiple myeloma - the first report of the DREAMM-3 phase 3 and long-term follow-up of the APOLLO phase 3 trial. Read the full article: https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00243-0/fulltext?dgcid=buzzsprout_icw_podcas…
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[00:01:05] Donating blood to purge toxic metals. Resources: Environmental pollutants in blood donors: The multicentre Norwegian donor study Blood donation and heavy metal poisoning in developing nations: Any link? Donor blood remains a source of heavy metal exposure [00:05:35] Andrew Huberman on seed oils: Twitter post. Layne Norton on seed oils: T…
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[00:00:51] Managing tendon pain. [00:02:06] Collagen (15g/day) and Vitamin C. [00:06:40] Wobenzym; Pure Encapsulations Systemic Enzyme Complex. [00:08:23] Healthy Gut Holozyme. [00:10:05] Factors that increase histamine at night. [00:15:52] Mast cell stabilizers: Quercetin, Spirulina, Black Cumin Seed Oil, Bromelain Resources: Histamine Elimination…
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[00:07:11] SIBO yogurt. [00:08:02] Book: Super Gut: A Four-Week Plan to Reprogram Your Microbiome, Restore Health, and Lose Weight 1, by Dr. William Davis. [00:08:13] Lactobaccillus rhamnosus GG. [00:15:24] Plant Therapy essential oils. [00:16:09] Hyaluronic acid. [00:30:00] Book: Tripping Over the Truth, by Travis Christofferson. [00:31:27] Podcas…
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Dr Eric Ohuma joins us to tell us about a study recently published in The Lancet Haematology on the association between maternal haemoglobin concentrations and maternal and neonatal outcomes. Read the full article: https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00170-9/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhae Continu…
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[00:00:25] Continuous glucose monitoring - a good idea for people without diabetes? Forum discussion. Resources: Imprecision nutrition? Duplicate meals result in unreliable individual glycemic responses measured by continuous glucose monitors across three dietary patterns in adults without diabetes. Effect of a plant-based, low-fat diet versus an a…
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[00:02:25] Keto diet and bone health; Article: A Short-Term Ketogenic Diet Impairs Markers of Bone Health in Response to Exercise. [00:12:09] Meta-analysis: Effects of the ketogenic diet on bone health: A systematic review. [00:18:52] Book: Tripping Over the Truth, by Travis Christofferson. [00:20:39] Balancing magnesium and potassium. [00:26:21] C…
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[00:01:57] Central nervous system (CNS) fatigue with power lifting and other sports. Resources: Central and Peripheral Fatigue in Physical Exercise Explained: A Narrative Review [00:07:18] Probiotics for dogs. Resources: Modulation of the intestinal microbiota of dogs by kefir as a functional dairy product [00:10:38] Relationship between Atrial Fib…
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[00:01:08] OLED televisions: less blue light? Resources: Effects of Organic Light-Emitting Diodes on Circadian Rhythm and Sleep Effects of Evening Exposure to Light from Organic Light-Emitting Diodes on Melatonin and Sleep Metabolic responses to polychromatic LED and OLED light at night [00:03:48] Timing carbohydrates consumption around exercise; m…
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Professor Margaret Ragni joins us to discuss the VWDMin study, published in The Lancet Haematology. In this phase 3, randomised, crossover trial, recombinant von Willebrand factor and tranexamic acid are used to treat heavy menstrual bleeding in patients with mild and moderate von Willebrand disease in the USA. Read the full article: https://www.th…
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[00:01:41] Filtering water: pros and cons. [00:02:12] EWG’s Water Database. [00:03:05] Choosing a filter system. [00:04:47] Timing a cold plunge with strength training. Resources: Post-exercise Cold Water Immersion Effects on Physiological Adaptations to Resistance Training and the Underlying Mechanisms in Skeletal Muscle: A Narrative Review The Ef…
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Dr Odejide and Dr Kuczmarski tell us about a study recently published in The Lancet Haematology on the effect of pre-existing mental health conditions on survival in patients with diffuse large B-cell lymphoma. Read the full article: https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(23)00094-7/fulltext?dgcid=buzzsprout_icw_podcast_gen…
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Professor Alok Srivastava tells us about two clinical trials being published in The Lancet and The Lancet Haematology on a new siRNA therapy called fitusiran for patients with haemophilia A and B. Read the two trials: Efficacy and safety of fitusiran prophylaxis in people with haemophilia A or haemophilia B with inhibitors (ATLAS-INH) https://www.t…
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Dr Emmanuela E Ambrose tells us about the SPHERE trial on hydroxyurea dose escalation for primary stroke prevention in children with sickle cell disease in Tanzania Read the full article: Hydroxyurea with dose escalation for primary stroke risk reduction in children with sickle cell anaemia in Tanzania (SPHERE) Continue this conversation on social!…
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Girls are having a rough go of it. A recent CDC report found 57% of teen girls felt persistently sad and hopeless in 2021, compared to 36% in 2011. Not only that, but a report last year found girls going to the ER for eating disorders nearly doubled during the pandemic. There’s never been a more important time to help support our daughters, both em…
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Dr Sumit Gupta discusses how racial and ethnic disparities affect survival outcomes of children and young adults with acute lymphocytic leukaemia. Read the full article: Racial and ethnic disparities in childhood and young adult acute lymphocytic leukaemia Continue this conversation on social! Follow us today at... https://twitter.com/thelancet htt…
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We’ve all seen the article or social media post declaring the “proven” benefits of intermittent fasting. Cellular repair. Improved insulin sensitivity. A longer life with reduced risk of chronic disease. Increased metabolism and fat burning. Because of these strong claims, I’ve been wanting to do a deep dive on intermittent fasting for years now. S…
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Professor Xiao-Jun Huang discusses this Lancet Haematology series on Cellular Therapy in China, covering the history, current research challenges, and future of HSCT and CAR T-cell therapies in China. Read the Series papers: Cellular therapy in China Continue this conversation on social! Follow us today at... https://twitter.com/thelancet https://i…
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Dr Glenn Pierce discusses the World Federation of Hemophilia’s Humanitarian Aid Program which provides access to haemophilia care in low-income and lower-middle-income countries. Read the full Review: Achieving access to haemophilia care in low-income and lower-middle-income countries Continue this conversation on social! Follow us today at... http…
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Eat well, exercise, and sleep is all we seem to hear about. But there is another important yet underrated factor for health: breathing exercises. Yep, the way we breathe can have a tremendous impact on our health in either direction–especially the duration and quality of sleep. This is vital as we age, making midlife the perfect time to invest in y…
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Dr Amy DeZern discusses the link between myelodysplastic syndrome and autoimmune disorders and the need for a multidisciplinary approach for the treatment of patients who have both. Read the full article: Myelodysplastic syndrome and autoimmune disorders: two sides of the same coin? Continue this conversation on social! Follow us today at... https:…
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Does it really take 66 days to build a healthy habit? Will there be a time we gain enough self-control or willpower to always eat nutritiously and exercise? My podcast guest turns everything we thought we knew about healthy behavior change on its head. Not only that, but she also has the research to support it. And a new book. Michelle Segar, PhD, …
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Dr Nicholas Crombie and Professor Gavin Perkins discuss their randomised phase 3 trial in which they investigated resuscitation with blood products compared with saline in patients with trauma-related haemorrhagic shock receiving prehospital care. Continue this conversation on social! Follow us today at... https://twitter.com/thelancet https://inst…
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Women talk about lots of topics, but vaginal health isn’t typically one of them. Yet midlife is the perfect time to start the conversation because most women will experience vaginal issues. In fact, 60 percent of menopausal women have vaginal symptoms like dryness, and this goes up to 80% post-menopause. But it’s not just about some annoying sympto…
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Dr Fredrik Schjesvold discusses the results of the OCEAN phase 3 trial testing melflufen or pomalidomide plus dexamethasone for patients with multiple myeloma refractory to lenalidomide. Read the full article: Melflufen or pomalidomide plus dexamethasone for patients with multiple myeloma refractory to lenalidomide (OCEAN) Continue this conversatio…
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Intuitive eating is needed more than ever during midlife. That’s because it helps redefine a woman’s relationship with food in ways that create sustainable change. Whether it’s listening to your body, avoiding all or nothing thinking about food, or denouncing diet culture, as my guest says: “it’s really something that needs to come together for mos…
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Dr Jacob D Soumerai and Prof Andrew D Zelenetz discuss their phase 2 trial of the BOVen regimen and MRD-driven treatment discontinuation in previously untreated patients with chronic lymphocytic leukaemia or small lymphocytic lymphoma. Read the full article: https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(21)00307-0/fulltext Continu…
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Dr Raul Cordoba discusses the joint Series between The Lancet Healthy Longevity and The Lancet Haematology on haematological malignancies in older people. Read the full article: A comprehensive approach to therapy of haematological malignancies in older patients Continue this conversation on social! Follow us today at... https://twitter.com/thelanc…
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Professor Obiageli Nnodu and Dr Dennis Chao join acting Deputy Editor Emma Cookson to talk about their new study describing modelling of child mortality as a result of sickle cell disease in Nigeria. Read the full article: https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(21)00191-5/fulltext Continue this conversation on social! Follo…
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Senior Assistant Editor Ben Burwood speaks with Dr Zuguo Mei (Division of Nutrition, Physical Activity, and Obesity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA) and Dr Gary M Brittenham (Department of Pediatrics, College of Physicians and Surgeons, Columbia Unive…
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Whether people realize it or not, the pandemic has shed a very bright light on nutrition. And this light tells us that an overwhelming number of Americans have comprised nutritional status putting them at higher risk of severe disease from Covid-19. Even more disturbing is that we are doing very little about it. In episode 34 of The Healthy Family …
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