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Back Bay Life Science Report

Jonathan P. Gertler and Peter Bak

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Back Bay Life Science Advisors brings you expert insights from our advisors and investment bankers in the world of BioPharma & MedTech. On this podcast, you’ll hear from our experts in life science development, commercialization, and investment banking, scientific investigators, biotech and medtech executives, physicians, and strategists who excel at guiding global life sciences companies and their investors through complex decisions. Join us for insights generated from in-depth scientific, ...
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Khwezi Science Report

TimesLIVE Podcasts

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The Khwezi Science Report is a dive into the warm waters of science where information is made interesting and understandable and is placed in the context of our daily lives. From archaeology to tech, astronomy to zoology, you'll find it all here with host Tanya Farber, a senior reporter at the Sunday Times. She loves how science connects with other ways of understanding the world around us from all sorts of disciplines. Each episode takes the listener on a journey through all things weird an ...
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Get your weekly burst of scientific illumination from The Debrief’s network of rebellious journalists as they warp through the latest breaking science and tech news from the world of tomorrow. Every Tuesday, join hosts Stephanie Gerk, Kenna Hughes-Castleberry, and MJ Banias as they roundup the latest science and tech stories from the pages of The Debrief. From far-future technology to space travel to strange physics that alters our perception of the universe, The Debrief Weekly Report is mea ...
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On this week's episode, Kenna and Stephanie learn to play an ancient Aztec "death whistle" and freak everyone out. They then go to battle some giant "Red Monsters" discovered by astronomers using the James Webb Space Telescope. They then shake down a new electrical technology that uses motion to power everyday devices. Every Tuesday, join hosts Ste…
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….or at a podcast with at least an attempt at an explanation of what synaptic density is and how it is affected in brains of people with autism. This week we review three convergent lines of evidence – whole brain, brain cell then genes within those brain cells – that show that the autistic brain has a decrease in cell-to-cell communication in mult…
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The topic of bispecific antibodies has been an area of interest in the pharma space for a long time now. The recent news of the notable late-stage data from Akeso and Summit’s PD-1/VEGF bispecific antibody ivonescimab to treat non-small cell lung cancer that has captured the industry writ large encouraged us to revisit the topic. To date, there hav…
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On this week's episode, Kenna and Stephanie decide to take a dip in a Martian ocean and discuss China's Mars expedition, and its discovery. After watching a movie and discussing brain science, they then wrestle an ancient terror bird to the ground, and ruminate on this giant fossil discovery. Every Tuesday, join hosts Stephanie Gerk, Kenna Hughes-C…
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Are you the grandparent, cousin, aunt, uncle, sibling, or half-sibling of someone with autism and wondered “what is the likelihood of autism in families, and the likelihood of comorbid conditions if I have a family member with autism?” Researchers at the AJ Drexel Autism Research Institute and Aarhus University in Denmark collaborated to calculate …
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On this week's episode, Kenna and Stephanie root around the swamp looking for mysterious "Swamp Dweller" fossils. They then discuss how a new discovery in Mexico using LIDAR has uncovered Mayan ruins, and a new opitical technology that could transform how we communicate in deep space. Every Tuesday, join hosts Stephanie Gerk, Kenna Hughes-Castleber…
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Despite many years fighting it, families with autism still experience societal stigma. The experiences depend on many factors, summarized in the October 21st podcast. This week, Mia Kotikovski explores cultural factors involved in stigma. As examples, she explores the literature from Asia, the Middle East and the United Kingdom, how they are differ…
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On this week's episode, Kenna and Stephanie dive deep into Norse mythology and the "Well-man." They then sing a tune and discuss how music, according to a new study, seems to have some healing capabilities, and that the now extinct Tasmanian Tiger may not be extinct for much longer. Every Tuesday, join hosts Stephanie Gerk, Kenna Hughes-Castleberry…
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Animal models of autism, including cell based models, have received criticism because autism is a uniquely human condition so there is no value in studying it in a model like a mouse or a cell. On the other hand, model systems have been used for decades to develop therapies for a myraid of other conditions and disorders, and produced evidence-based…
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On this week's episode, Kenna and Stephanie don't find the droids they're looking for, but instead come across a bizarre study about mice and how they may be able to "smell" with sound. So, are mice actually Jedi in disguise? Stephanie then takes great pleasure in learning that her coffee addiction may actually be keeping her alive, and Kenna explo…
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This week, part 1 in cultural stigma around autism with Mia Kotikovski provides an overview of stigma, where it can come from across cultures and provides some examples of stigma in different countries. Different areas of the world are in different places in terms of their perceptions of autism, their needs for autism families, and what they percei…
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On this week's episode, Kenna and Stephanie get flipped upside down discussing Earth's magnetic field reversal. They then dive deep underwater to chat about a strange "Frankenstein" sea creature, and touch on a robotic finger developed in China. Every Tuesday, join hosts Stephanie Gerk, Kenna Hughes-Castleberry, and MJ Banias as they round up the l…
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Understanding factors that make each person with autism different has been a challenge, affecting diagnosis, interventions and the way we think about autism in general. Researchers at Istituto Italiano di Tecnologia, Rovereto, Italy, used computers to see how language, intellectual ability, motor and adaptive functioning grouped individuals into di…
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On this week's episode, Kenna and Stephanie run around the sea floor with a fish that has evolved to taste with its feet. They then veg out and discuss some vertical farming innovations, and how Germany wants to fuel its country one balcony at a time. Every Tuesday, join hosts Stephanie Gerk, Kenna Hughes-Castleberry, and MJ Banias as they round up…
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A few years after the start of the pandemic, and a couple of years into “recovery”, scientists are still disentangeling the effects of COVID-19 lockdowns and exposure. For example, is there an uptick in autism screen positives when pregnant mothers fell ill? Were there diagnostic disparities based on co-morbid conditions? Did autistic people feel b…
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In this DNB//Back Bay Healthcare Capital Markets Episode, Vasilios Kofitsas, Partner and Managing Director at Back Bay Life Science Advisors speaks with Jim Cirenza and Kristoffer Braaten of DNB Bank in New York. They focus on key drivers affecting markets this year and discuss the recent news of the Fed’s decision to cut interest rates by 50-basis…
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In part 2 of the GI series in ASD, a new paper in the Journal of Nutrition and Gastroenterology describing the www.candidgi.com meeting is described. While sometimes doctors may be know-it-alls, sometimes they do not know-it-all and need experts to advise them, especially when they encounter individuals who may be hard to diagnose and treat. Those …
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In this bonus episode of the DWR, Steph and Kenna invite quantum physicist and best-selling author Chris Ferrie on the show to speak about how to explain quantum physics to all audiences, where the media gets quantum wrong, and how quantum influences learners of all ages. Every Tuesday, join hosts Stephanie Gerk, Kenna Hughes-Castleberry, and MJ Ba…
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In the first of a two-part series on digestive health in ASD, Mia Kotikovski summarizes scientific information about what the complicated microbiome is, how it influences physical and psychiatric health, if it is altered in autism, and what causes it to be different in ASD. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638778/ https://www.frontiers…
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On this week's episode, Kenna and Stephanie slay while discussing how the popular role playing game Dungeons and Dragons can positivly impact people with autism. Following a close call with a troll, they discuss the science behind "out of body experiences." The two hosts then swarm a new study concerning Japanese eels, and the long awaited video ev…
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After a summer away from podcasting, Back Bay Life Science Advisors’ Dr. Pete Bak and Christian Thienel are back on the mic to discuss current market dynamics in liver disease with a focus on one of the most closely watched space in hepatology, MASH. The big news includes a rebrand from NASH (non-alcohol related steatohepatitis) to MASH (metabolic …
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On this week's episode, Kenna and Stephanie become totally clear on a new method that can turn living skin transparent. They then discuss some shocking new research on whether gold can make electricity and how a new type of "biohybrid" robot is changing our understanding of robotics. Every Tuesday, join hosts Stephanie Gerk, Kenna Hughes-Castleberr…
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New research points to a previously understudied but fascinating mechanism by which environmental factors may lead to autism: it’s called the “GABA/glutamate switch” which is a critical period in development when certain cells turn from turning on cell activity to turning them off. These environmental factors may delay this process leading to long …
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On this week's episode, Kenna and Stephanie dip their toes into a story about Chinese scientists who say they have found a way to produce water on the Moon. They then take a long look into deep space and the discovery of six new "rogue planets" by the James Webb Telescope. Finally, they discuss a new smart window technology, and its ability to gene…
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In this bonus episode of the DWR, Steph and Kenna invite astrophysicist, aerospace engineer, and science fiction consultant, Dr. Erin Macdonald to share her insights in the world of astrophysics and Star Trek. The trio discuss how science advising works for television, and the state of science today. Every Tuesday, join hosts Stephanie Gerk, Kenna …
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Stephanie and Kenna are back for a new season of The Debrief Weekly Report. In this episode, they take a mental dip into new findings regarding "hidden consciousness" inside the brain. They also discuss why playing video games is good for your mental well being, and a brand new bandage that uses water and electrical currents to heal wounds faster! …
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This week, special correspondent Mia Kotikovski discusses challenges in getting emergency care for those with autism, what doctors and hospitals can do to ease the stressors associated with places like the ER. This is a huge issue for families as many “simple” ER visits for their autistic family members can cause such stress it provokes … Continue …
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Instead of grouping together people with autism based on traditional severity scores, what if groupings were done based on functional outcome? Would this help better understand the broad spectrum of autism and why some people with autism are so different than others? Researchers at the University of Minnesota led by Kyle Sterrett, together with UCL…
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During sleep, your brain is still active. It is turning all those things you learned during the day into long term memories through connections between the thalamus, hippocampus and frontal cortex. What happens in Profound Autism? How does the brain work during sleep and how will this knowledge lead to better sleep in people? Are … Continue reading…
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In part 1 of a 3 part series on Profound Autism, ASF interviews Emily Ferguson, PhD from @Stanford shares what she learned by asking parents and caregivers of Profound Autism “what do you need?” The short answer was: “There is No Help“. The responses were overwhelmingly focused on inclusion in any program or service, since … Continue reading "What …
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What is the probability of having a future child with autism if you already have one or more? Families want to know. It helps preparation, planning, will hopefully improve early screening and supports. The Baby Siblings Research Consortium analyzed a bigger group of siblings compared to their 2011 numbers and found the recurrence pretty stable … Co…
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In case you missed it, listen to Alison Singer with Gina Kavali on her podcast @LifeWiththeSpectrum. Alison talks about the importance of autism research and science in general, and how families can get involved.द्वारा Autism Science Foundation
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On this week’s podcast, Mia Kotivkoski, founder of her own 5013c and recent graduate of Stony Brook University, reviews why understanding cultural and contextual factors influence not just an autism diagnosis but general health and outcomes of a broad group of people. They include immigrants, racial and ethnic differences, and socio-economic factor…
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Join Stephanie and Kenna for the last episode of the season as they discuss a new nano robot developed in Sweden that can kill cancer cells in mice. They also open a channel to the ISS and discuss how NASA is using laser relays to send photos and messages to astronauts. Lastly, they take a trip and talk about how a new study says that micro-doses o…
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This week, more on genetics as an influence to an autism diagnosis with a twist: can genetics lead to a specific treatment for core symptoms – across the board? How do you measure such broad symptoms? Our Rett Syndrome family friends and colleagues developed a novel outcome measure to capture what was most important to … Continue reading "Breakthro…
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In this week’s episode of the DWR, Stephanie and Kenna discuss NASA's plan to build an artificial star for astronomical measurements. They also explore a lost Greek temple mentioned in ancient graffiti, and a new black hole discovery using magnetic winds to feed. Every Tuesday, join hosts Stephanie Gerk, Kenna Hughes-Castleberry, and MJ Banias as t…
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Very rarely are scientists able to look at single genes within the brains of people across neuropsychiatric disorders and understand how the genes in each of these cells influence expression of proteins and interactions of different cells with each other. Recently, a collaboration called PsychENCODE released a series of papers that investigated wha…
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In this week’s episode of the DWR, Stephanie and Kenna go green as they discuss a novel breakthrough in the successful generation of electricity by algae. The dynamic duo also discuss the Einstein Telescope and the discovery of the lost ship, The Quest, off the coast of Newfoundland, Canada. Every Tuesday, join hosts Stephanie Gerk, Kenna Hughes-Ca…
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In recognition of Father’s Day on the 16th, today’s podcast includes the latest research on fathers. Fathers may often be the “secondary caregiver” but should hardly be dismissed as inconsequential. Father’s sensitivity and insightfulness plays an important part in development, psychiatric diagnoses (including autism) change the the chance of havin…
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In this week’s episode of the DWR, MJ and Kenna discuss the successful 3D printing of metal material on the ISS. The dynamic duo also dives into the first-ever Master’s Degree in Psychedelics offered at the University of Ottawa and a new metal coating that changes regular glasses into night-vision goggles. Every Tuesday, join hosts Stephanie Gerk, …
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General psychiatrists are trained deal with a range of psychiatric issues in a variety of areas, but very few have experience helping families of children and adults with autism. This is training that is desperately needed, as, like other professions, there are not enough psychiatrists to help families and waitlists are staggering. Dr. Arthur Westo…
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Scientists have spent a lot of time trying to understand the biology of autism, unfortunately in the past, scientific studies had everyone with autism lumped together in one group and there are so many differences between people with a diagnosis that any features of the diagnosis itself were hard to detect. In the past, researchers … Continue readi…
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In the fourth bonus episode of the DWR, Steph and Kenna discuss the Star Wars Expanded Universe and its impact on fan experiences. The dynamic duo also dives into how the expanded universe has helped bring in more fans, creating a multigenerational experience. Every Tuesday, join hosts Stephanie Gerk, Kenna Hughes-Castleberry, and MJ Banias as they…
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In this DNB//Back Bay Healthcare Capital Markets podcast episode, learn about the key considerations, mechanics and timelines of going public on a US exchange. Topics in this podcast include: An overview of the decision-making process through execution for US-based and ex-US healthcare companies thinking about listing in the US Core considerations …
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On this week's episode of The Debrief Weekly Report, Kenna and Steph seek out the lost settlers of the Roanoke colony, and new research that may have solved the riddle of what happened there all those years ago. Things also get hot when they discuss a new solar power system that can generate tons of heat, and how false memories are becoming much mo…
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While NDBIs are generally considered beneficial, they still face controversies – do they actually work and does that translate to an improved quality of life for the family? This week’s #ASF podcast interviews Molly Reilly and Jinwei Song of @UConn to dive into these issues, as well as the role of the caregiver in the … Continue reading "Are Natura…
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On this week's episode of The Debrief Weekly Report, Kenna and Steph dive head first into a lava tube in Saudi Arabia that once served as a human dwelling. They also discuss how a new swarming technology can be used to clean up microplastics and other pollutants in our oceans, and recap on the wild solar storm that hit Earth over the weekend. Every…
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A legend in the autism community passed away on Friday. Today’s podcast focuses on the many talents of Dr. James (Jim) Simons, one of the founders of the Simons Foundation that has spent more than $500 million on autism research. We explain how he made his fortune, how he spent it, the importance of the … Continue reading "Rest in Power Jim Simons"…
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On today’s episode, Kenna and Stephanie stare into the eyes of an ancient Neanderthal, explore who she was, and how scientists were able to reconstruct her face. They also dive deep into underground Chinese forests inside giant sinkholes, and the mysterious Roman dodecahedrons. Every Tuesday, join hosts Stephanie Gerk, Kenna Hughes-Castleberry, and…
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As health care and outcomes for very premature infants has improved, scientists are able to track their longer term behavioral development, and that includes risk of developmental disorders like autism. On this week’s #ASFpodcast, Dr. Jessica Bradshaw discusses her recent research examining biological predictors like body temperature and heart rate…
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